For LAN, no. If you have a router NAT’ting traffic and providing DHCP service there’s really no need for ipv6. Almost every ipv6 enabled service provides both 6 and 4 usually and NAT figures it out, and many still provide only 4, meaning you can’t just get rid of ipv4 entirely.

If your ISP has modernized and is actually providing an ipv6 address, I suppose there’s probably a tiny benefit of being able to go ipv6>ipv6 when routing, bust most all devices nowadays can handle NAT translation from ipv4 to ipv6 and vice versa with no routing penalty. I don’t know if there are any ISP’s out there who can provide static ipv6 addresses without a NAT router to your entire LAN though.

If you’re buying a vps or something ipv6 is easier to get a static address for.

That of course leaves the last good reason: why not? If you’re doing homelab hosting stuff why not experiment with ipv6 and fully modernize your network. They suck to type in but it’s fun to know your stuff is brand new and using the “best”.