Takatakatakatakatak

I keep looking at maps and wondering how Ukraine haven’t been routed and cut off in enemy territory with no supply lines. What they’re doing seems borderline insane but more power to them!

She treated herself

Seems like a fair and reasonable response to a cartoon.

The religion of peace strikes again.

I’ve been wanting these guys to chill for over 20 years. They have no chill. I’ve read so many takes on what it is they actually want, and why they keep seizing power. It seems the actual answer is that they just want power. Plain and simple.

Neither of them represents an acceptable choice to lead a party. That’s kind of my point.

If these are the only two viable candidates then something is completely broken and needs to change.

I don’t understand how they can possibly put Biden forward again. He’s well past losing his marbles. Way too old to run imo. It’s disgraceful.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2976712/

It’s significant. Biggest effect is on efficacy of drug metabolism. There are many such studies.

One size does not fit all here owing to differences in expression of metabolising enzymes and drug transport mechanisms.

No, the Japanese are not aliens but they may require far less of a given drug than a westerner, or far more. This affects the likelihood to experience side effects for any given compound, and their severity.

It’s fairly ironic to make this change for Japan whilst elsewhere in the world with more racially mixed populations there has been a push in the opposite direction: a recognition that you cannot assume the results of a trial carried out on white male subjects will apply to those of African descent for example.

It’s not just drug treatments either. There are many aspects of medical care which have suffered from a lack of specificity and systemic bias.

I know enough to believe this isn’t a great idea.

Genetic variation in target populations can result in different outcomes for a variety of treatments and is worth testing specifically.

Sorry about the grainy, difficult to read image. I am on mobile and couldn’t find a better version right now.

I think you might have misunderstood one of the primary internet rules “There are no girls on the internet.”

If you squint, you’ll work it out.

https://i.imgur.io/f2rLQ_d.webp?maxwidth=640&shape=thumb&fidelity=medium

My money is on a devout Jewish gentleman offended that women had some kind of representation anywhere.

That Lemmit bot that just keeps posting links to Reddit has got to go!!

If it’s worth posting or discussing, link the original article and make your own damn post. I don’t want a link back to Reddit.

Even for the photoshop, I need context right fucking now!

I’m mad that you all keep giving them traction by engaging with this toxic shit.

Everyone is well aware of their motivations, but keep falling for it anyway. This is a wedge issue.

We have a winner.

Drag shows are not a real issue, no. You constantly engaging with it as if it is one is exactly what these fuckers want.

You are being distracted. Focus. You CAN eat your local representative. One bite at a time.

People don’t need to know what is in the chilli at the cookout.

Nah, maybe just that it is fuckall business of government and they should concentrate on real issues instead of poking their nose into what clothes people wear?

I for one am fucking sick of hearing about this particular subject. Why is anyone talking about this?

It seems like you’ve read enough to get halfway there.

You should go back and read the source documents and go over what ecohealth alliance were actually doing, and where they were doing it. The funding proposals were extremely detailed, right down to carrying out gain of function research to aerosolise the corona viruses harvested from bats.

It is almost impossible to immunise bats using droplet transmission and this is the source of the global fuckup.

At some stage during this process, the modified pathogen from very early stages of developing a corona vaccine FOR BATS (the stated goal of the funding request) it somehow got out of one of the labs involved. (Malice or stupidity, we’ll never know)

At that stage it would still be fair to call the original escaped variant a VIRUS because it had not yet reached the development stage of being attenuated sufficiently to be called a vaccine, but it was a long way from a wild type variant.

This lines up with early sequencing of the virus that is widely documented. Those with any scientific integrity have acknowledged from day 1 that there were portions of the sequence that can not occur without human intervention.

In short, this was all being done with US funding in labs with woefully inadequate safety protocols.

So long as we are prepared to accept the risk/reward profile of gain of function research being carried out anywhere in the world, the risk of a similar global pandemic will never go away.

Have you considered the possibility that any deep state actors (that may or may not exist) actually crave the type of destabilizing force that Trump represents?

Counter to the fairlytales, a country divided is a country easily ruled.

If you can sew enough division, using fear as a weapon is much easier.

What better pawn to install as President than Donald fucking Trump?

They knew his debts. They knew the people who had dirt on him. They knew he was incompetent. They knew he was easily controlled. They knew he was for sale.

This isn’t rocket science and I’m pretty sure history will eventually prove me right. He’s a weak little piece of shit. A dog that does as he’s told by his masters, including the current line to tow in his definitely 100% real legal dramas.

It’s all theatre. Barely better acted than American wrestling.

Your former president is simultaneously fighting to stay out of prison whilst doing his best to run for president again? Please.

Vince McMahon would be proud.